Vitamins/Minerals Archives | Experience Life https://experiencelife.lifetime.life/category/nutrition/vitamins-minerals/ Mon, 06 Oct 2025 20:11:56 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.2 A Look at LTH Dream: Natural Sleep Support Without Melatonin https://experiencelife.lifetime.life/article/a-look-at-lth-dream-natural-sleep-support-without-melatonin/ Thu, 07 Aug 2025 13:00:28 +0000 https://experiencelife.lifetime.life/?post_type=article&p=121822 This non-habit-forming evening drink mix can support deep, restorative rest with science-backed ingredients like magnesium, ashwagandha, L-theanine, and phosphatidylserine.

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Sleeping well is one of the most essential things we can do for optimal health, recovery, and overall well-being. Yet for many of us, a good night’s sleep can feel as far from reality as a dream.

Estimates show that 47 percent of people in the United States currently take something to help them with sleep. This is concerning, as sleep is our body’s most significant tool for recovery, mental clarity, and long-term health. Getting poor sleep is not just an inconvenience — it can wreck our health.

Not getting enough of the right kind of sleep can lead to cognitive impairment, mood issues, weakened immune function, fat gain, metabolic issues, increased cardiac risk, hormone issues, poor exercise recovery, and accelerated signs of aging. There is no such thing as optimal health without optimal sleep, no matter how dialed in your exercise and nutrition might be.

But because many of us struggle to get enough — whether in terms of quantity or quality or both — we may seek out tools for support. Many first turn to over-the-counter sleep aids, and while there is a time and place for those, I find many are unaware that these options typically work by sedating us. This doesn’t improve sleep physiology or optimize good sleep architecture, which are required to feel and perform at our best.

In addition to prioritizing good sleep hygiene practices (more on those below), there are a few supplement options that I frequently recommend to clients, including  one I’m particularly enthusiastic about — LTH Dream. This multi-magnesium sleep-support supplement can also be part of a nightly wind-down routine, another impactful habit experts tout for supporting sleep.

A Closer Look at LTH Dream

It Starts With Magnesium

The No. 1 nutrient many of us need to focus on for optimal sleep is magnesium. Magnesium deficiencies or suboptimal levels are highly prevalent, which can have a variety of health effects, including on insulin regulation.

When magnesium levels are suboptimal, your body can’t regulate blood sugar well. And if your body doesn’t regulate blood sugar well, the ups and downs you may experience during the night can impact the quality of your sleep.

Magnesium is crucial for physiological relaxation, too. It not only helps muscles and nerves function and relax, but it is also intimately involved in mental health and the ability to regulate and unwind.

Repleting magnesium alone can often be the ticket to sleeping better, though the form of the mineral you take is important. The most absorbable forms are chelated, meaning they’re wrapped in amino acids, and these can be significantly more beneficial for sleep than some of the cheaper forms of magnesium.

LTH Dream stands out with the inclusion of three different forms of magnesium:

  • Magnesium taurate: Combines magnesium with taurine to help calm the nervous system, support GABA activity, and ease the transition into restful sleep.
  • Magtein® magnesium L-threonate: A patented form of magnesium developed at MIT that’s uniquely able to cross the blood-brain barrier. It’s been shown in clinical studies to enhance deep sleep and REM sleep, reduce nighttime awakenings, and support mental clarity upon waking.
  • Magnesium bisglycinate: A gentle, chelated form of magnesium paired with glycine to promote relaxation and help reduce sleep latency (the time it takes to fall asleep).

Note: All forms of magnesium used in LTH Dream — and the entire LTH supplement line — are chelated.

Targeted Ingredients Give it a Boost

LTH Dream is specifically formulated to promote deep rest and recovery for the brain and body, as well as to help build resilience, support a healthy cortisol rhythm, and optimize cognitive health. In addition to the multiple forms of magnesium in therapeutic doses, these other ingredients are also worth highlighting:

  • Sensoril® ashwagandha: A standardized, clinically studied adaptogen (adaptogens are a category of ingredients that can support a healthier stress response). Sourcing for adaptogens is important, and this form is known to be both tested and trusted for quality. It helps reduce cortisol and support sleep onset and quality.
  • L-theanine: A calming amino acid, L-theanine promotes alpha brain waves for mental relaxation without drowsiness. It can often work synergistically with magnesium to help reduce mental chatter, ease tension, and support better focus and stress resilience the next day.
  • Phosphatidylserine: This is a vital phospholipid that is found in cell membranes of mammals and supports healthy brain cell communication; it plays a key role in memory, focus, and cognitive performance. For many, it can also act like a pump on the breaks for your HPA axis, or adrenal system, for stress.

LTH Dream is melatonin-free, non-habit forming, and is naturally flavored and sweetened; it’s available in mixed berry and piña colada flavors. Like all other LTH supplements, it undergoes extensive testing to ensure what’s on the label is what’s in the bottle.

How to Use LTH Dream

LTH Dream was designed to support those who have trouble staying asleep, don’t feel rested upon waking, prioritize their athletic performance and repair, or have interrupted sleep they can’t control (such as if you have young kids, are a caregiver, or do shift work). Since it’s not artificially sedating and instead supports healthier physiological sleep patterns, most can still rouse if and when they need to.

LTH Dream comes in a powder form. Mix one level scoop into 10 to 12 ounces of water — we recommend whisking, shaking, or using a frother — within an hour or so before going to bed. To make it feel like a nighttime mocktail experience, I like to pour mine into a fancy glass and garnish with a piece of fruit.

We always recommend checking with your physician before starting any type of new supplementation; LTH Dream may not be suitable for children, those who are pregnant or breastfeeding, or those taking certain medications (such as sleep medications, antibiotics, sedatives, or Alzheimer’s medications).

What Are Some Helpful Steps in a Nightly Sleep Routine?

These are some simple habits I recommend that can make a difference in your body’s readiness for bedtime:

  • Start in the morning. Your body’s circadian clock runs on 24-hour cycles, and if you’re able to prioritize getting at least 10 minutes of sunshine first thing in the morning, it can go a long way toward helping your body know when “daytime” starts in order to better understand “nighttime.”
  • Keep a regular schedule. Pick a bedtime and waketime you can be consistent with across weekdays and weekends. Ideally, these times will allow you to get seven to nine hours of rest per night.
  • Stop caffeine intake 10 to 12 hours before bed. The half-life of caffeine in healthy adults is up to seven hours. This means that if you drink a cup of coffee at 3 p.m., 50 percent of it could be in your system at 10 p.m.
  • Shut off electronics one to two hours before bed. Limit exposure to the blue light that emits from your devices. Their light mimics sunlight and the stimulation it can cause.
  • Implement a nightly ritual. Having consistent bedtime routine can signal to your body that it’s to wind down. For instance, LTH Dream can serve as a night cap. Pair it with washing your face, brushing your teeth, and changing into your pajamas and you’ve got a simple ritual that can help you prepare for sleep.

(To hear more from Samantha McKinney on how to safely supplement to support sleep, listen to her Life Time Talks podcast episode, “Why Supplementation for Sleep?”)

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A glass with LTH Dream resting on sheets on a bed.
How to Eat for Eye Health https://experiencelife.lifetime.life/article/how-to-eat-for-eye-health/ https://experiencelife.lifetime.life/article/how-to-eat-for-eye-health/#view_comments Mon, 23 Jun 2025 13:01:23 +0000 https://experiencelife.lifetime.life/?post_type=article&p=116026 When it comes to eating for healthy eyes, carrots are just the beginning. Discover the best nutrients for eye health.

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Many of us spend the first half of our lives assuming that if we can see, our eyes are healthy. Then we spend the second half expecting our vision to falter.

“Only when things start to go wrong do people stop taking their vision for granted,” says Rudrani Banik, MD, an integrative eye doctor in New York City and associate professor at Mount Sinai Icahn School of Medicine. She’s also the author of Beyond Carrots: Best Foods for Eye Health A to Z.

Yes, aging changes the eyes. The lenses stiffen, making it difficult to read menus in low light and identify the buttons on the TV remote. But beyond the common need for reading glasses, aging does not necessarily lead to poor vision.

“A lifetime of simple choices, such as what you eat and what you wear in the sun, not only reduces the risk of developing an eye disease but also mitigates the extent of disease if it does happen,” says Neda Gioia, OD, CNS, IFMCP, an integrative optometrist in Shrewsbury, N.J.

According to the Centers for Disease Control and Prevention, four in 10 American adults are at high risk for vision loss. The most common causes are cataracts, glaucoma, diabetic retinopathy, and age-related macular degeneration. All are likeliest to develop after age 50.

Still, we’re not helpless. “Studies have shown that the best thing you can do to support the overall health of your eyes is to make healthy nutrition choices,” Banik says.

The more colorful your food choices, the better. In the plant kingdom, color signals antioxidants, and antioxidants are your eyes’ bulwark against free-radical damage.

That protection is vital. While the eyes are relatively small organs, visual processing involves a lot of brain power: An estimated 50 percent of the brain’s cortex is devoted to the visual pathways, Banik notes. This processing uses a lot of energy, which leads to free-radical production.

The cells inside the retina are so metabolically active that pieces of the rods and cones constantly break off and need to be hauled away, explains optometrist Jeffrey Anshel, OD.

“Think of it like taking out the garbage,” he says. “If debris builds up, the system breaks down.”

Antioxidants, especially a subset called carotenoids, are the eye’s trash collectors. The natural world bursts with hundreds of varieties of these bright plant pigments, but only a few dozen have woven their way into the human diet. Even fewer shoulder the outsize role of cleaning up after the eyes. If the volume of trash chronically overwhelms the available carotenoids, vision can get glitchy.

But stocking up on carotenoids isn’t difficult. Turn to these nutrients to maintain long-term ocular health.

Anthocyanins

→  Best sources: Bilberries and other berries

→  Most important effect: Targets light-induced oxidative stress in ocular tissue

Anthocyanins — the pigments that give berries their bright reds, deep purples, and near-black blues — have a storied reputation for sharpening vision.

During World War II, British pilots reportedly ate bilberry jam to enhance their night vision. Although postwar studies didn’t find convincing evidence that bilberries support better ­vision at night, scientists have noted the berries’ capacity to soothe digital eyestrain.

In recent studies, people who significantly upped their intake of anthocyanins reported improvement in the telltale sensations of eyestrain after they’d concentrated on a screen for up to an hour. This included relief from fatigue and blurred vision.

Other studies suggest bilberry extract might alleviate the symptoms of DED. Bilberries are high in delphinidin-3,5-O-diglucoside, an anthocyanin that limits free-radical formation in the tear glands. This helps lubricate the eyes and the surface of the cornea.

blueberriesBerries also have a low glycemic index, making them especially beneficial for people with diabetes, which often leads to vision damage. When blood-sugar levels are erratic, the spikes and drops can damage the blood vessels that lie on top of the retina, says Anshel. “Eventually, the blood vessels break down, which can cause blurry vision or even blindness.”

Bilberry extracts are largely safe, especially when consumed in amounts that approximate a serving or two of the berries themselves.

Astaxanthin

→  Best sources: Shrimp, salmon, and lobster

→  Most important effect: Protects against dry-eye disease

Astaxanthin is the carot­enoid responsible for the reddish-pink tint of salmon, shrimp, and lobster. ­Although less well studied than other carotenoids, astaxanthin is one of the strongest anti­oxidants found in nature. It has up to 1,000 times the potency of vitamin E, 200 times that of tea polyphenols, and 10 times more than lutein or zeaxanthin.

“Effectively, it is a super­antioxidant,” says Gioia. “It is a powerful player in the carotenoid family.”

It also plays a very specific role in eye health. Astaxanthin minimizes oxidative stress and downregulates ­inflammatory cytokines around the glands that lubricate the eyes. Without enough moisture, the eyes ­become susceptible to dry-eye disease (DED). This condition — characterized by irritation, burning, and stinging — affects up to a third of people over 50.

In a study published in Frontiers in Nutrition, 60 ­patients with mild to moderate DED experienced significant improvements after taking 6 mg of astaxanthin tablets twice daily for about 30 days.

Research on astaxanthin supplementation is relatively thin, so for now, food sources are your best bet. (Try these astaxanthin-rich recipes for salmon, this Spicy Ginger Shrimp Sheet-Pan Meal, or this elegant grilled lobster).

Glutathione

→  Best sources: Avocados and asparagus

→  Most important effect: Protects the lenses from oxidation

avocadoOur eyes’ lenses are bombarded with high-intensity, shortwave blue light for much of the day. Sunlight is a huge source of oxidative stress, as are computer screens.

To protect itself, the pea-size lens has one of the highest concentrations of glutathione found anywhere in the body.

Glutathione is often called the master antioxidant, but “superhero” is more accurate. It can ­regenerate after neutralizing free radicals and wields enough power to bring other exhausted antioxidants, like vitamin E, back to life.

“Glutathione is essential for keeping oxidative stress in check,” says Banik.

The glutathione we produce naturally declines as we age, so researchers are exploring whether a lack of the nutrient leaves the eyes more vulnerable to ­oxidative stress and, therefore, age-related vision troubles. Several studies have found asparagusdecreased levels of glutathione in patients with age-related macular degeneration, but the mechanisms are still not understood.

Because glutathione supplements are poorly absorbed through the gut, the best way to boost levels is by enjoying a variety of antioxidant-rich vegetables and fruits. In addition to avocados and asparagus, sulfur-rich crucifers like kale, cabbage, and broccoli, as well as alliums like onions, garlic, and shallots, are good choices.

(Learn more about this power antioxidant and how you can boost your levels at “8 Ways to Boost Glutathione.”)

Lutein and Zeaxanthin

→  Best sources: Kale, spinach, and eggs for lutein; goji berries for zeaxanthin

→  Most important effect: Protects the retina from blue light

Two carotenoids are nonnegotiable for eye health: lutein and zeaxanthin. Differing only in their arrangement of atoms, they contribute to the bright red, orange, and yellow pigments found in plants.

These nutrients are unique in their ability to cross the blood-retina barrier to reach the macula, a small part of the retina that’s responsible for central vision. Once there, they concentrate in the retina’s center to take the brunt of the sun’s high-intensity, short-wavelength blue light. Banik describes them as nature’s sunglasses.

Our bodies can’t make carotenoids, so we need to get them from food. Lutein resides in dark leafy greens, broccoli, and egg yolks. Less-plentiful zeaxanthin is found in corn, persimmons, and orange peppers. Fun fact: The food with the most ­zeaxanthin is the goji berry.

| Fun fact: The food with the most ­zeaxanthin is the goji berry.

While shielding the retinas from blue light, lutein and zeaxanthin also increase contrast, boost visual acuity, lower oxidative stress, and cool inflammation. Gioia says the importance of lutein and zeaxanthin to ocular health is unequivocal. Aim to eat dark leafy greens and eggs several times a week (see “How to Eat More Dark, Leafy Greens” for ideas on how to add more to your diet).

An egg yolk is lutein-rich, adds Anshel, so be sure to eat more than just the whites. He also suggests cooking greens in extra-virgin olive oil because fat increases the body’s absorption of these nutrients.

There is no official recommended daily intake for either lutein or zeaxanthin, but some research clocks a benefit with a daily 10 milligrams of lutein and 2 mg of zeaxanthin.

Worth noting is that the typical American diet includes just 1.7 mg of lutein a day, so you may want to consider taking a supplement. Multiple studies suggest lutein and zeaxanthin supplements can address mild vision complaints, like glare sensitivity, and help prevent more serious conditions, such as age-related macular degeneration.

Omega-3 Fatty Acids

→  Best sources: Oily fish and flaxseeds

→  Most important effect: Eases eyestrain

Best known for fighting inflam­mation, omega-3 fatty acids may also help alleviate DED and digital eyestrain.

Estimates suggest that up to 90 percent of people experience visual discomfort after spending time on screens. The most common complaints are eye soreness, headaches, and blurry vision.

Growing evidence also shows a connection between screen time and dry eyes. Blinking lubricates the eye, and normally we blink about 15 times a minute. Our per-minute blink rate plummets to a half or a third of that when we stare at a screen.

Fatty acids can help. The connection between DED and omega-3 fats was first established in 2005. Data from more than 32,000 participants in the Women’s Health Study found that those who consumed fatty fish multiple times a week slashed their DED risk by as much as 68 percent. In the 20 years since, several studies have suggested that supplementing with omega-3 fatty acids could significantly improve symptoms of DED.

Gioia suggests the acronym SMASH for identifying some of the fish richest in omega-3s: salmon, mackerel, anchovies, sardines, and herring. And omega-3s frequently travel alongside eye-supportive astaxanthin, as in salmon. “Salmon is a rich source of eye-healthy nutrients,” she says.

You can also protect against digital eyestrain by sitting an arm’s length from your screen, looking up and away from your screen at regular intervals, and opting for glasses instead of contacts.

(Explore this guide to understanding omega-3 and omega-6 fatty acids and how they influence your health.)

Vitamin A

→  Best sources: Sweet potatoes, carrots, and liver

→  Most important effect: Prevents night blindness and dry-eye disease

Vitamin A helps convert light energy into nerve energy inside the retina, says Anshel. Without ample vitamin A, the retina struggles to rebuild its rods and cones, specialized cells that respond to light and are essential for vision.

sweet potato slicesRods govern peripheral vision and operate in low light, enabling night vision; cones handle central vision, calibrating the color and high-intensity light that come with daytime.

In the retina, vitamin A forms rhodopsin, a light-sensitive protein that responds to light as it enters the eye.

Vitamin A deficiency is the leading cause of preventable blindness in children worldwide, but a milder deficiency may show up as nyctalopia (night blindness) or xerophthalmia (extremely dry eyes).

“The hardest thing we ask our eyes to do is drive at night,” says Anshel. The brightness of oncoming headlights contrasted against the darkness of the road forces the eyes to switch between prioritizing the cones and the rods. Abundant vitamin A makes that job easier.

Most of us get plenty of this nutrient from the beta-carotene — a carotenoid the body turns into vitamin A — in our diets (think carrots). There’s also vitamin A in fish, ­organ meat, dairy, and eggs. The recommended daily allowance for vitamin A is 700 micrograms for adult women and 900 mcg for adult men.

Too much vitamin A can be harmful, so if you supplement, take care not to exceed 3,000 mcg daily.

(Discover easy, flavorful ways to enjoy sweet potatoes plus six creative carrot recipes.)

Vitamin C

→  Best sources: Citrus, tomatoes, bell peppers, and kiwi

→  Most important effect: Protects the eyes from the sun

lemon and lime sliceAnother potent antioxidant, vitamin C is found throughout the body, but concentrations in the aqueous humor — the clear liquid in front of the eye’s lens — are up to 70 times greater than in plasma. This points to vitamin C’s importance in protecting the eyes from free-radical damage.

The lens is a unique structure in our bodies, says Anshel. “It requires oxygen to grow but has no blood supply because you can’t see through blood. The lens needs to be transparent so light can reach the retina.”

As we age, the lens continues growing ­— and as it grows, it thickens. The thicker the lens, the less flexible it becomes, which is why we lose the ability to focus on things up close, he notes.

grapefruitAnd without a blood supply, the lens must get all its nutrition through the aqueous humor.

Scientists suspect that the vitamin C in the humor shields lenses from UV damage, which in turn helps prevent cataracts, the leading cause of blindness worldwide.

Reaching the recommended 200 mg of vitamin C daily is easy if you eat at least five servings of vegetables and fruits, especially citrus, tomatoes, bell peppers, and kiwi. Since the body cannot absorb more than 250 mg of vitamin C a day, anything more than that will be flushed out in the urine.

(Vitamin C is an essential nutrient that supports nearly every aspect of health. Learn more at “What You Need to Know About Vitamin C.”)

This article originally appeared as “Eating for Eye Health” in the July/August 2025 issue of Experience Life.

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https://experiencelife.lifetime.life/article/how-to-eat-for-eye-health/feed/ 0 a variety of fresh foods that support eye health
The Powerful — and Surprising — Health Benefits of Melatonin https://experiencelife.lifetime.life/article/the-powerful-and-surprising-health-benefits-of-melatonin/ https://experiencelife.lifetime.life/article/the-powerful-and-surprising-health-benefits-of-melatonin/#view_comments Thu, 19 Jun 2025 13:01:48 +0000 https://experiencelife.lifetime.life/?post_type=article&p=116044 Melatonin is much more than a sleep compound. It helps to regulate hormones, boost immunity, and support mitochondria. Learn about the many roles it plays.

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The molecule of darkness. The hormone of rest and rejuvenation. The ultimate multitasker. These are just some of the ways nutrition scientist Deanna Minich, PhD, CNS, IFMCP, describes melatonin.

“When most people think of melatonin, they think of sleep,” says Minich. “They are unaware of its many other functions.”

Melatonin is a crucial part of the sleep cycle, but its role does not end there, she notes. “It’s a potent antioxidant, it regulates the mitochondria, it can stimulate the immune system, and it’s a circadian signal.”

And there’s more. Melatonin helps control temperature, blood pressure, and the gut microbiome. It also supports neurogenesis and protects nerve cells, which help repair and detoxify the brain.

“Melatonin is called nature’s most versatile biological signal,” Minich says.

Melatonin is a hormone found throughout nature, made by plants, animals, fungi, and even bacteria. In humans, most circulating melatonin is produced in the pineal gland from the amino acid tryptophan. The pineal gland responds to evening darkness by releasing melatonin into the bloodstream, telling the body it’s time for sleep.

On average, the pineal gland generates between 0.1 and 0.9 milligrams of melatonin per day. The gut mucosa contains about 400 times more, but most of it stays within the gastrointestinal tract. There it helps protect the gut lining, reduce inflammation, and regulate gut motility and the microbiome.

Melatonin is also synthesized in the eyes, skin, and various other glands and organs. At these sites, it helps modulate the immune system, repair tissue, and prevent oxidative stress and inflammation.

Our bodies start producing melatonin when we’re about 3 months old, with levels ramping up from infancy to adolescence and peaking ­before puberty. Production then declines and can drop significantly by the time we reach our 50s.

“This is when we find ourselves in ‘melatonipause’ — a term I love because it syncs up with the decline of so many other hormones,” Minich says.

In addition to aging, melatonin production is influenced by illness, diet, and environmental factors such as exposure to artificial blue light at night. Some medications and a lack of exposure to sunlight can also impact levels.

There’s a lot to know about this crucial molecule and the many ways it supports our health. Let’s explore some of melatonin’s more unexpected roles.

How Does Melatonin Fight Free-Radicals?

Free radicals are highly reactive molecules. They’re a natural byproduct of metabolism, but the body also produces them in response to nutritional deficiencies as well as ­exposure to ultraviolet radiation, pollution, certain medications, and toxins. There are ­always free radicals circulating in our bodies, but an excess of them can lead to cellular damage, chronic diseases, and accelerated aging.

Antioxidants neutralize harmful free radicals. Some, such as vitamins C and E, come exclusively from dietary sources. Others, such as glutathione, are mostly produced in the body (the superhero antioxidant, glutathione, battles toxicity, chronic disease, and premature aging. Find out what makes it so powerful at “8 Ways to Boost Glutathione.”)

Melatonin is an antioxidant that’s both produced in the body and ­derived from dietary sources — though we make more than we can get from food.

“Melatonin is a direct scavenger. It gobbles up free radicals like Pac-Man.”

“Melatonin is a direct scavenger. It gobbles up free radicals like Pac-Man,” says Russel Reiter, PhD, one of the world’s leading melatonin experts. “Vitamin E and vitamin C are go-to antioxidants, but they don’t compare to melatonin.”

Several factors make melatonin a potent antioxidant. First, unlike vitamins C and E, it’s both water- and fat-soluble, so it can move freely through all types of cells and tissues, offering protection throughout the body.

Second, because melatonin is produced within our ­cellular ­mitochondria, where free radicals are created, it can quickly neutralize troublemakers ­before they have a chance to do damage.

Finally, melatonin and its meta­bolites can scavenge up to 10 free radicals, while most antioxidants can vanquish only one.

Minich compares melatonin to a set of Russian nesting dolls. “When melatonin gets one free radical, it changes into the next doll down, which gets another free radical, et cetera. All of a sudden, 10 dolls later, it’s cleaned up quite a number of bad things in the body.”

Does Taking Melatonin Affect Circadian Rhythm?

Many of us mistake melatonin for a seda­tive, but it doesn’t induce sleep directly. Instead, it more broadly supports sleep by helping regulate our body’s internal clocks — the circadian rhythms.

In addition to the sleep–wake cycle, these rhythms govern hormone production, ­metabolism, immune function, and body temperature.

“Melatonin helps open the ‘sleep gate’ by lowering our core body temperature and preparing the brain for synchronizing with the peripheral clocks throughout the body,” Minich explains. “As it becomes dimmer and darker at night, our melatonin goes up, our core body temperature comes down, and we get this signal to head for bed.”

While melatonin supplements won’t knock you out on their own, they can assist if you struggle to fall asleep, especially if your internal clocks are dysregulated by shift work or travel. A ­Cochrane review published in 2002 concluded that 0.5 to 5 mg of melatonin is “remarkably ­effective in preventing or reduc­ing jet lag,” particularly for those traveling east.

Timing matters. If melatonin is taken early in the day, the review authors note, it can cause sleepiness too early and further confuse the body’s internal clock.

Some studies suggest that supplement­ing with 3 mg of melatonin can help ­menopausal women who struggle with nighttime hot ­flashes regulate their body temperature.

Does Melatonin Help Reduce Inflammation?

During the COVID-19 pandemic, melatonin received heightened attention for its capacity to both help fight infections and reduce inflammation. A paper published in Clinical Nutrition ESPEN in 2021 listed it among the key preventive and therapeutic nutraceuticals for COVID, along with zinc, selenium, and vitamins C and D.

Melatonin can stimulate cytokine production to help the body fight off invading viruses, bacteria, or other pathogens, notes John ­Lieurance, ND, DC, in his book Melatonin: Miracle ­Molecule. It can also help slow down cyto­kine production when the body needs to reverse or prevent potential inflammatory damage.

“Being chronically underslept will increase the likelihood of illness and chronic inflammation.”

“It is this dual action of melatonin on the immune system that has been of particularly great interest to scientists,” Lieurance writes. It makes melatonin especially valuable in treating conditions like COVID, where the potential overreaction of the ­immune system — known as a cytokine storm — can be as damaging as the infection itself.

Because inflammation is managed in part by optimal sleep, melatonin’s role in promoting sleep is key, says Samantha McKinney, RD, who helps lead nutrition education at Life Time. “Being chronically underslept will increase the likelihood of illness and chronic inflammation.”

Emerging research suggests that symptoms associated with inflammatory autoimmune conditions, such as multiple sclerosis, may be eased with melatonin supplementation. This is most likely due to the hormone’s anti-­inflammatory properties and its ability to reduce oxidative stress and regulate the gut microbiome.

How Does Melatonin Affect Mitochondria?

The pineal gland produces most of the melatonin that circulates through the body and regulates circadian rhythms. Another type of melatonin is produced inside our cells, by mitochondria. “Melatonin and mitochondria go together,” says Minich.

Known as the power­houses of our cells, mito­chondria produce energy in the form of adenosine triphosphate, which fuels virtually everything our cells do (learn more about these essential molecules and how to keep yours healthy at “The Care and Feeding of Your Mitochondria.”)

Because of their role in energy production and cellular health, mitochondria also influence how we age. Dysfunctional mitochondria can contribute to cellular senescence — the loss of a cell’s ability to divide and function properly. Senescent cells release inflammatory signals, driving much of the chronic inflammation and tissue damage associated with age-related decline.

Mitochondrial dysfunc­tion has been linked to neurodegenerative diseases like dementia, Alzheimer’s, Parkinson’s, and multiple sclerosis. Poor mitochondrial health can also contribute to type 2 diabetes, cardio­vascular disease, and psychiatric disorders.

The presence of melatonin and other antioxidants in mitochondria is key to preventing such dysfunction and damage. “Now we know that melatonin is synthesized in the mitochondria, and it seems to be very efficient at protecting mitochondria from damage,” Reiter says.

How Does Melatonin Affect Your Immune System?

The body’s immune system protects us from harmful viruses and bacteria. It also identifies and destroys mutated human cells that can ­develop into cancer. Melatonin ­increases the level of circulating natural killer cells, which bolsters the immune system’s ability to ward off diseases ­including colds and cancer.

As of 2024, more than a hundred studies on PubMed pointed to the potential of melatonin in supporting treatment for a range of cancers, ­including breast, prostate, and bladder. ­Melatonin supplementation, which has been used for decades in ­patients under­going chemotherapy, “seemed to sensitize the cancer cells to the treatment,” Minich says.

Is Melatonin Healthy for the Brain?

Thanks in part to its sleep-supportive properties, melatonin plays a critical role in brain health.

“One of the main ways sleep protects the brain is by supporting the glymphatic system, which helps detoxify the brain nightly,” McKinney explains. As we sleep, this system flushes out metabolic waste products that contribute to neurodegenerative diseases such as Alzheimer’s.

Melatonin is an important molecule in this “brainwashing” process, as Reiter calls it. As a sleep-regulating hormone, it enhances deep, restorative sleep — when the glymphatic system is most active.

Melatonin’s antioxidant powers protect brain cells from oxidative stress and inflammation, both of which accelerate cognitive decline. Because it’s both ­water- and fat-soluble, it can cross the blood-brain barrier and directly neutralize harmful free radicals in the brain.

Melatonin’s presence in the brain can lead to cognitive benefits, especially for people with neurodegenerative conditions like ­Parkinson’s. It may even help with neuropathic pain and depression risk, Minich says.

She sometimes calls melatonin the ­“molecule of consciousness” because it can enhance the vividness of dreams, and she notes that long-term meditators have been found to have higher levels of melatonin compared with nonmeditators.

Given melatonin’s many positive roles, it’s only natural to wonder about your own levels. Melatonin can be measured in the blood, saliva, and urine, but Reiter says these metrics are of limited utility.

“It’s very difficult to find your own melatonin levels, because you have to get the nighttime values,” he explains. “If you go to your physician and ask to be tested, we’ll all have low melatonin because daytime levels are always low.”

“It’s very difficult to find your own melatonin levels, because you have to get the nighttime values. If you go to your physician and ask to be tested, we’ll all have low melatonin because daytime levels are always low.”

Our levels can also vary day to day, month to month, and season to season.

“It’s better to look at symptoms,” Minich says. Some indicators of insufficient melatonin include:

  • abnormal fatigue
  • inflammatory conditions
  • chronic stress
  • gut dysbiosis
  • frequent colds or infections
  • disrupted sleep patterns

You can also review your cur­rent circumstances. Stress, inconsis­tent sleep patterns, and nighttime light exposure can all suppress melatonin production.

And age matters: Around 40, natural production of the hormone begins to decline more steeply.

Paying attention to your symptoms and circumstances — and supporting melatonin production by maintaining a consistent sleep schedule, limiting blue-light expo­sure at night, and spending time in natural daylight — can help you reap melatonin’s many benefits.

Strategies for Supplementing With Melatonin

Melatonin is widely available as a supplement, with doses usually far exceeding what our bodies make naturally ­— even when production is at its peak. Circumstances such as cancer treatment warrant taking high doses under a physician’s care, but for most of us, less is more, says Deanna Minich, PhD, CNS, IFMCP.

“We produce less melatonin as we get older, so I think a physiological dose of 0.3 to 1 milligram is reasonable to ‘patch the gap,’” she says.

Research supports her suggestion. An older MIT study determined that 0.3 mg of melatonin was more effective at treating insomnia than the typical drugstore dose of 3 mg. It also found that the higher dose elevated circulating melatonin levels during the day, causing a hangover effect.

For jet lag, however, the reverse is true. Studies suggest that a dose of 5 mg helps people fall asleep faster and sleep better than 0.5 mg but that more than 5 mg had no additional benefit.

For daily use, Minich recommends starting with 0.3 mg, taken about 30 to 60 minutes before bedtime. If you feel groggy in the morning, you may need to take it earlier, about two to three hours before bed.

She also recommends opting for plant melatonin over synthetic versions. A study published in Molecules in 2021 found the plant-derived molecule in the brand Herbatonin to be more anti-inflammatory and better at free-radical scavenging. (Minich is the chief science officer for Symphony Natural Health, which produces Herbatonin and whose cofounder helped author the study.)

Melatonin supplements aren’t for everyone. They can interact with medications, including blood thinners, blood-pressure drugs, and immunosuppressants. And anyone who is pregnant, breastfeeding, or managing a hormone-related or autoimmune disorder should speak with their healthcare provider before use.


This article originally appeared as “Melatonin’s Many Wonders” in the July/August 2025 issue of Experience Life.

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I’m Pregnant. How Much Iodine Do I Need? https://experiencelife.lifetime.life/article/im-pregnant-how-much-iodine-do-i-need/ https://experiencelife.lifetime.life/article/im-pregnant-how-much-iodine-do-i-need/#view_comments Fri, 13 Jun 2025 13:00:00 +0000 https://experiencelife.lifetime.life/?post_type=article&p=115769 If you’re pregnant or nursing, here's what you need to know about iodine intake.

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If you’re pregnant or nursing, you’ll need more iodine to support the health and ­development of your child. Iodine deficiency in ­pregnancy can result in ­maternal and fetal hypothyroidism, as well as in miscarriage and preterm birth.

Insufficient ­iodine intake is considered the most common preventable cause of delayed brain development. “It’s fundamental to a healthy baby,” says April Lind, MD, a board-certified internal-medicine, pediatrics, and functional-medicine physician.

A developing baby’s thyroid gland doesn’t start making thyroid hormones until the second trimester of pregnancy. During pregnancy, your free T4 thyroid hormones contribute to the baby’s total thyroid hormone levels. Further, babies are born with little stored iodine and “rely on breast milk or infant formula to meet their iodine needs to continue making T4,” writes Malini Ghoshal, RPh, MS, in The Iodine Balancing Handbook.

To accommodate these requirements, the RDA for iodine increases to 220 mcg per day during pregnancy and 290 mcg per day while nursing.

Anyone who’s pregnant, planning to get pregnant, or lactating should supplement their diet with 150 mcg per day of iodine in the form of potassium iodide to ensure they meet these minimum levels.

Anyone who’s pregnant, planning to get pregnant, or lactating should supplement their diet with 150 mcg per day of iodine in the form of potassium iodide to ensure they meet these minimum levels, according to the American Thyroid Association, the Endocrine Society, and the American Academy of Pediatrics.

Still, because the window of tolerance is so small, many experts suggest talking with your doctor before adding supplemental iodine to your diet.

“Pregnant women are also more sensitive to big shifts in iodine,” writes Ghoshal, ­referencing a study suggesting that “women who consumed more iodine-rich foods and who took an­ ­iodine-containing multi­vitamin had higher urine iodine levels and higher incidences of thyroid disorder than those with low or even more than adequate iodine levels.”

Understanding the Role of Iodine

We need just the right amount of iodine for health — not too little, not too much. Learn how to strike a balance at “Why Iodine Is Important for Your Health,” from which this article was excerpted.

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How Much Iodine Do I Need? https://experiencelife.lifetime.life/article/how-much-iodine-do-i-need/ https://experiencelife.lifetime.life/article/how-much-iodine-do-i-need/#view_comments Fri, 06 Jun 2025 12:00:22 +0000 https://experiencelife.lifetime.life/?post_type=article&p=115766 It doesn't take a lot to meet your daily requirement of this essential nutrient, but there a few important things to be aware of. Learn more.

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The recommended daily allowance (RDA) of iodine for adults who are not pregnant or breastfeeding is a mere 150 micrograms. The upper intake level — the maximum daily amount considered safe — is 1,100 mcg, or just over 1 milligram.

“It’s been called the Goldilocks mineral,” says Christianson. “For most nutrients, you have a much bigger buffer zone than that.”

The iodine you consume in food and drink is absorbed in your gut and circulated through your blood. If your iodine intake is sufficient, only 10 percent of circulating iodine is brought into your thyroid; the rest is excreted in your urine within 24 to 48 hours.

In healthy adults, the thyroid concentrates and stores enough iodine to meet your body’s requirements for two to three months. It sends out a tiny amount of iodine per day, about 80 mcg, to make thyroid hormones.

If you routinely fall short on iodine, your thyroid gradually stops producing enough thyroid hormone to support your health.

Understanding the Role of Iodine

We need just the right amount of iodine for health — not too little, not too much. Learn how to strike a balance at “Why Iodine Is Important for Your Health,” from which this article was excerpted.

The post How Much Iodine Do I Need? appeared first on Experience Life.

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Can I Learn My Iodine Status? https://experiencelife.lifetime.life/article/can-i-learn-my-iodine-status/ https://experiencelife.lifetime.life/article/can-i-learn-my-iodine-status/#view_comments Fri, 30 May 2025 12:00:00 +0000 https://experiencelife.lifetime.life/?post_type=article&p=115773 It's tricky. Here's why and what you need to know.

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If you experience symptoms of thyroid disease, your practitioner may assess your iodine levels. But unless you ­receive a full thyroid workup, getting an accurate ­measurement of your own iodine level can be tricky.

“There are many tests available for iodine, but none of them are perfect … because there’s so much variability from reading to reading,” says Alan Christianson, NMD, author of The Thyroid Reset Diet.

Some tests, such as spot urine iodine elimination tests, are good for providing a snapshot of population health, but they’re not accurate for assessing individual iodine levels. Other urine iodine tests can be used for individuals but are often burdensome and expensive.

“The best way of understanding somebody’s iodine status is a dietary ­history,” says Lind.

Understanding the Role of Iodine

We need just the right amount of iodine for health — not too little, not too much. Learn how to strike a balance at “Why Iodine Is Important for Your Health,” from which this article was excerpted.

The post Can I Learn My Iodine Status? appeared first on Experience Life.

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Why Is Iodine Controversial? https://experiencelife.lifetime.life/article/why-is-iodine-controversial/ https://experiencelife.lifetime.life/article/why-is-iodine-controversial/#view_comments Fri, 23 May 2025 12:00:02 +0000 https://experiencelife.lifetime.life/?post_type=article&p=115771 Learn about the complexity of balancing this essential nutrient and why it matters to your health.

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Some integrative-health practitioners see the recent rise in thyroid-related diseases — including hypothyroidism and thyroid cancer — as evidence that we need more ­iodine than public health guidelines suggest.

“Many feel the current adult RDA of 150 mcg per day was provided as a baseline to prevent goiter and is not an appropriate level for ideal iodine balance to allow for its full range of benefits,” explains Malini Ghoshal, RPh, MS.

Some also argue that our increased exposure to the iodine-blocking effects of halogens (including chlorine) and halides (such as fluoride) may require us to consume dramatically more iodine in order to push out these blockers and free up iodine-receptor sites.

But an approach like this can pose dangers, especially to people with hyperthyroidism, hypothyroidism, or autoimmune thyroid conditions such as Graves’ disease.

“If you have a preexisting thyroid condition or have experienced iodine deficiency in the past, you may be more vulnerable to thyroid disorders … if you take in too much iodine,” explains Ghoshal. “This may happen even with small increases in iodine intake, but it’s particularly risky if you’re exposed to high levels of iodine for a long time or experience an iodine overdose.”

This increased vulnerability may be due to something called the Wolff-Chaikoff effect. “Basically, your thyroid has a safety switch,” explains Alan Christianson, NMD, author of The Thyroid Reset Diet, in a blog post. “If too much iodine comes in, rather than make lethal amounts of thyroid hormone, your thyroid shuts off. It is a great example of homeostasis and has been used … to slow the thyroid when it is overactive.”

For most people, the Wolff-Chaikoff effect reverses once iodine levels normalize, but for people with thyroid problems, it can be permanent.

Christianson recommends that people avoid iodine supplements, and he views universal iodization to prevent goiter as an overcorrection. He points to research that suggests universal salt iodization has increased hypothyroidism, hyperthyroidism, and autoimmune thyroiditis in susceptible populations.

“The paradox is that populations that run on the low side of iodine have the lowest rates of autoimmune thyroid disease,” he states.

“The benefits and the harms of iodine are a U-shaped curve,” adds April Lind, MD, a board-certified internal-medicine, pediatrics, and functional-medicine physician.. “If you have too little, it’s a problem; and if you have too much, it’s a problem.”

Understanding the Role of Iodine

We need just the right amount of iodine for health — not too little, not too much. Learn how to strike a balance at “Why Iodine Is Important for Your Health,” from which this article was excerpted.

The post Why Is Iodine Controversial? appeared first on Experience Life.

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What Is Iodine, Exactly? https://experiencelife.lifetime.life/article/what-is-iodine-exactly/ https://experiencelife.lifetime.life/article/what-is-iodine-exactly/#view_comments Fri, 09 May 2025 12:00:36 +0000 https://experiencelife.lifetime.life/?post_type=article&p=115758 There's more to this essential nutrient than you may realize. Learn more.

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Iodine is an essential micronutrient — “essential” in that it’s required for your body to function, but your body doesn’t make it, so you can get it only through your diet. Iodine supports virtually every aspect of health, primarily by helping create thyroid hormones. Iodine also has antioxidant, anti-infection, and potential anticancer properties.

A trace mineral, iodine is found in seawater as well as in certain rock formations and soil. Erosion and flooding have depleted soil iodine in many areas of the world, which has led to widespread iodine deficiencies and helps explain why iodine levels in food are so inconsistent (more on this later).

If you look at the periodic table of elements, you’ll see iodine is a halogen, a category that also includes bromine, chlorine, and fluorine. Halogens and halogen-based compounds, called halides, are often used in commercial cleaning products, as well as in pharmaceuticals and food additives. ­Research has found that exposure to some of these halogen-containing compounds can block the absorption of iodine in the thyroid. However, experts disagree about how much everyday exposure may threaten thyroid health — and what to do about it.

“Iodine is unusual in a lot of ways,” says Alan Christianson, NMD, author of The Thyroid Reset Diet. “It’s a high-energy atom. It’s further down on the periodic table than anything else we use nutritionally, so it’s chemically reactive. It has the capacity to trigger a great number of chemical reactions in the body.”

Understanding the Role of Iodine

We need just the right amount of iodine for health — not too little, not too much. Learn how to strike a balance at “Why Iodine Is Important for Your Health,” from which this article was excerpted.

The post What Is Iodine, Exactly? appeared first on Experience Life.

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How to Eat for Good Gut Health https://experiencelife.lifetime.life/podcast/how-to-eat-for-good-gut-health/ Tue, 25 Mar 2025 10:00:53 +0000 https://experiencelife.lifetime.life/?post_type=podcast&p=114505 The post How to Eat for Good Gut Health appeared first on Experience Life.

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Why Supplementation for Sleep? https://experiencelife.lifetime.life/podcast/why-supplementation-for-sleep/ Tue, 11 Mar 2025 10:00:01 +0000 https://experiencelife.lifetime.life/?post_type=podcast&p=113212 The post Why Supplementation for Sleep? appeared first on Experience Life.

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